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PSM-ABS Job and Internship Board

This web page is the student’s resource for current job openings and internship opportunities.

To get a head start on your search, please be sure you have a current curriculum vitae (CV) or resume ready, as well as a list of good references who could vouch for your skills, integrity and academic achievements.

 

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Overview of the company

Icagen partners with pharmaceutical and biotechnology companies to offer industry-leading scientific expertise and comprehensive access to technologies for ion channel and transporter drug discovery and development. With over 20 years of leadership in the ion channel field, the Icagen team offers an extensive track record of success in advancing molecules from drug discovery to clinical development across multiple therapeutic areas and ion channel classes.

Announcement received: 09.16.16

Start – Fall semester 2016 ASAP

Aim –Investigate strategies to increase muscle stem cell activity, both proliferation and differentiation, for future therapeutic intervention in muscular dystrophies. Objectives for each student are to gain experience in muscle stem cell culture and master experimentation in the early drug discovery space. Students will gain experience in advanced analytical techniques and skills relevant in assaying cellular biology function.  Completion of these projects will aid student(s) in future academic or industry career paths.

Position 1 - Investigate cellular signaling pathways in isolated muscle stem cells (satellite cells).

The student will learn and perform muscle stem cell culturing and passaging. Multiple techniques will be utilized including differentiation of muscle stem cells, quantification of gene expression via quantitative Real-time PCR, quantification of protein expression via immunohistochemistry, and analysis of high content imaging. Project timeline is 3 months.

Position 2 - Investigate microRNA function in muscle stem cells.

The student will learn and perform muscle stem cell culturing and passaging. The student will utilize transient transfection methods to knock-down and inhibit expression of microRNA's of interest in muscle stem cell culture. Multiple techniques will be utilized including differentiation of muscle stem cells, quantification of protein expression via immunohistochemistry, and analysis of high content imaging.  Project timeline is 3-6 months.

Position 3 - Investigate small molecule modulation of muscle stem cell biology, early drug development.

The student will learn and perform muscle stem cell culturing and passaging. The student will evaluate multiple small molecules targeting signaling pathways of interest. Multiple techniques will be utilized including differentiation of muscle stem cells, quantification of gene expression via quantitative Real-time PCR, quantification of protein expression via immunohistochemistry, and analysis of high content imaging. Project timeline is 3-6 months.

Required Experience

• Cell culture and aseptic technique

For more information, please contact:

L. Charlie Chen (CChen@icagen.com)
Senior Research Investigator
Icagen Tucson Research Center
2090 E Innovation Park Dr
Oro Valley, AZ  85755
Phone: (520) 544-6868

Last updated 20 Jun 2017